I have been down on multivitamins for a long time. Most of them have totally ridiculous ratios of essential nutrients and completely miss out on important ones like Magnesium and Calcium. They tend to be poor quality and don't absorb well. Often times they don't provide any nutrition and can actually make you feel ill or leech nutrients from your body.
Mira and Jayson Calton have release a product called Nutreince and I have to say I am REALLY impressed. I haven't taken a mutli in over 10 years and recently wrote an article for the Daily Beast about how you can use supplements as tools and take them as needed. I still believe that for the more unusual and special supplements but my eyes have been opened to how wide spread micronutrient deficiency really is.
Even if you eat really healthy, which can be defined in any number of ways, you are still not going to get the nutrients you need. The Caltons looked at various popular diets to see how much of these essential nutrients they provide, such as Vitamin A, E, K, D, Calcium, Magnesium, and about 20 others. The best performing diet was the Paleo diet and it was only 52% sufficient. Meaning you would need to consume about 17,000 calories per day on that diet in order to get all of the vitamins you need. I can tell you from eating eating 9,000 calories a day for Ironman training, 17,000 is literally impossible. Due to soil depletion, transportation, processing, cooking methods, stress in our bodies, and environmental factors we simply can not get everything we need from food. These deficiencies can be linked to any number of acute and chronic conditions.
There are two really smart things about the way Nutreince is designed. First off it's a powder so you don't have to worry about swallowing a ton of pills, which you would need to in order to get the same amount of vitamins (especially magnesium which is very dense) and the packets are divided in two, one for the morning and one for the evening. They do this because vitamins compete with each other. For instance, Calcium and Magnesium compete for the same receptors in your body so they make it impossible to fully absorb both at the same time. These are in separate packets. In addition, Magnesium has a calming, sleep promoting effect, so why would you take it in the morning? I've been using the vitamins for just a short while now and I can already feel a difference in my energy levels and sleep quality (which of course I quantify using a variety of devices).